Bacillus Calmette-Guerin (BCG) immunotherapy for bladder cancer: Current understanding and perspectives on engineered BCG vaccine
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چکیده
منابع مشابه
Bacillus Calmette-Guerin (BCG) lymphadenitis-changing trends and management.
BACKGROUND Bacillus Calmette-Guérin (BCG) vaccination is performed as a part of expanded Programme of Immunization (EPI). Suppurative lymphadenitis is the common complication of BCG vaccination. The optimum treatment for this complication is debated. METHODS All cases of BCG lymphadenitis presenting to pediatric surgical service over a 17-year study period were reviewed to determine the optim...
متن کاملPricing and Reimbursement Analysis of Bacillus Calmette-Guérin (BCG) Immunotherapy for Bladder Cancer.
RESULTS According to the European Association of Urology (EAU) Guidelines for non-muscle invasive bladder cancer (NMIBC) bladder preservation strategies available include: intravesical immunotherapy, intravesical chemotherapy, device-assisted therapy and combination therapy. In Serbia, there are three medicines listed for chemotherapy (doxorubicin, epirubicin and mitomycin) and one for intraves...
متن کاملBacillus Calmette-Guérin (BCG) Infection Following Intravesical BCG Administration as Adjunctive Therapy For Bladder Cancer
Bacillus Calmette-Gu erin (BCG) is the most effective intravesical immunotherapy for superficial bladder cancer. Although generally well tolerated, BCG-related infectious complications may occur following instillation. Much of the current knowledge about this complication comes from single case reports, with heterogeneous diagnostic and therapeutic approaches and no investigation on risk factor...
متن کاملBacillus Calmette-Guerin and bladder cancer.
Bladder cancer is the second most common cancer of the urinary tract, and overall it is among the top 10 cancers in men. Transitional cell carcinoma (TCC) is the most common type, with the majority being superficial disease, i.e. the tumour has not gone beyond the lamina propria. The main problem with superficial TCC is the high recurrence rate. Various forms of treatment methods have been atte...
متن کاملBCG Prevention of the Recurrence of Bladder Cancers Prevention of the Recurrence of Superficial Bladder Cancers: Intravesical Instillation of Bacillus Calmette-guerin Versus Bacillus Calmette-guerin Plus Epirubicin
Purpose The short-term effects of intravesical chemoimmunotherapy with epirubicin and Bacillus CalmetteGuerin (BCG) administered repeatedlly for prophylaxis of recurrence of superficial bladder cancer (pTa, pT1) were investigated in 22 patients with a median of 70 years between March, 1995 and February, 1999, and were compared with those of BCG monotherapy in 50 patients between March, 1995 and...
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ژورنال
عنوان ژورنال: Cancer Science
سال: 2013
ISSN: 1347-9032
DOI: 10.1111/cas.12075